AlphaFold is a tool that predicts a protein's 3D shape, and its confidence score tells us how likely each part is to be correct. As a policy maker, I see this score not as pure truth, but as a guide for where to spend our limited lab funds for validation—we cannot chase every high-score prediction. In my ledger, a perfect balance on paper still needs the weight of actual coins in the hand; similarly, a confident prediction needs wet-lab confirmation. So we prioritize verification for structures related to public health crops, because I have seen how the grain merchants' accounts can look perfect until the monsoons ruin the stock.
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