Peripheral tolerance is the body's ledger, where immune cells learn not to attack our own tissues, with regulatory T cells acting as careful auditors. Anergy is like a transaction being voided—a cell rendered inactive—and FOXP3 mutations show the system's entire formula failing. Yet, we trust this internal accounting to balance itself. My own bhalu ignored years of joint pain, a self-tolerance that turned against me, and I now see that a system meant to protect can also hide a growing debt until the columns no longer add up.
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